Aldactone belongs to the subgroup of potassium-sparing diuretics. It affects hormone aldosterone which regulates the water balance of the body, accelerates potassium excretion and prevents a strong excretion of sodium and water. The higher the level of aldosterone, the more water accumulates in the body. Aldosterone antagonist is spironolactone, its use can reduce the level of aldosterone in the body and thereby increase excretion of sodium and water body, which simultaneously leads to the accumulation of potassium. With the help of spironolactone (we have it more often sold under the name “Veroshpiron”) of potassium in the body do not accumulate. Like other diuretics, it also displays the potassium from the body. Just in smaller quantities. Therefore, it is called potassium-sparing diuretics. A small loss of potassium is there, but it is relatively easily compensated by sravneniyub stop loss of potassium, which we have seen, say, tiazidevyh diuretics. Therefore aldactone along with current analogous triamterene (Direniumom) and amiloride (Midamorom) constitute a group of potassium sparing diuretics that act on the body much “smoother” than other groups of diuretics – thiazides and “looped agents” (saluretiki).
What should definitely pay attention of departure, taking aldactone (or other potassium-sparing diuretics), because it is the fact that in parallel should not take potassium chemicals, as it can lead to life-threatening increase potassium levels in the body.
Note that aldactone possesses antiandrogenic properties, thereby reduces androgen levels in blood. Bodybuilders use it Adaktona property in order to minimize the phenomenon of masculinization at the steroid “courses”, as well as for the return of femininity after them. Men have another problem: because changing ratio-androgens, estrogens in favor posleny, often accompanied by reception aldactone events in men are painful swelling of the nipple until gynecomastia.
Other possible accompanying reception aldactone adverse effects: low blood pressure, muscle cramps, dizziness, gastrointestinal disorders, vomiting, irregular heartbeat, weakness. However, the side effects of potassium-sparing diuretics compared to thiazide and “stitch agents” are manifested significantly less.
Because aldactone reception does not adversely affect instantly see the effects of dehydration, athletes start taking it for 1-2 weeks before the event. The most common dose – 50 mg per day.